Lisinopril/hydrochlorothiazide, sold under the trade name Zestoretic among others, is a combination of the medications lisinopril, an ACE inhibitor, and hydrochlorothiazide, a diuretic. It is used to treat high blood pressure. Typically it becomes an option once a person is doing well on the individual components. It is taken by mouth. Lisinopril is in a class of drugs called angiotensin-converting-enzyme (ACE) inhibitors. This medicine is used to lower blood pressure, to treat congestive heart failure and to improve the survival rate after a heart attack. Depron Foam provides a selection of Depron types and depths for use with insulation and modelling purposes, Free next day delivery on all Depron products Lisinopril is used to treat hypertension, congestive heart failure and to improve survival after a heart attack. Learn about side effects, interactions and indications. Hypertension. Lisinopril tablet USP is indicated for the treatment of hypertension in adult patients and pediatric patients 6 years of age and older to lower blood pressure. Find patient medical information for Lisinopril Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Lisinopril works to reduce blood pressure by blocking the formation of angiotensin II, a hormone that usually helps to keep blood pressure high, and decreasing blood volume. Lisinopril is used alone or in combination with other medications to treat high blood pressure. It is used in combination with other medications to treat heart failure. Lisinopril (Zestril, Prinivil, Qbrelis) is an ACE inhibitor drug used to treat elevated blood pressure and heart failure and to improve survival after heart attack. Side effects include a non-productive cough, nausea, insomnia, and sexual dysfunction. Drug interactions and pregnancy and breastfeeding safety information is included. Medical uses. Lisinopril is typically used for the treatment of high blood pressure, congestive heart failure, acute myocardial infarction (heart attack), and diabetic nephropathy.